Health Desk – 30 Apr, 2021: The Russian developer of the Sputnik V coronavirus vaccine said on Thursday it would sue the Brazilian health regulator Anvisa for defamation, prompting a stern rebuttal from the agency.
Anvisa’s board on Monday denied requests by Brazilian states to approve Sputnik V for import. The agency’s manager for medicines and biological products, Gustavo Mendes, said there was evidence an adenovirus used in the vaccine could reproduce, which he called a “serious” defect.
Adenoviruses – a category of viruses that can cause a range of illnesses in humans like the common cold – are sometimes repurposed as viral vectors for vaccines. Such viral vectors are often used to transport genetic material for a protein – in this case, from the novel coronavirus – to elicit an immune response from vaccinated individuals.
However, global health guidelines warn against “replication-competent adenoviruses” (RCA) that could multiply inside a patient’s body, possibly creating a negative reaction.