August 5, 2017: Molecular sector is gradually growing in Bangladesh. In near future, disease diagnosis will depend on molecular sector. Practices of molecular techniques are going good in some of the universities like Shahjalal University of Science & Technology (SUST), University of Dhaka (DU) etc.
Some hospitals and diagnostics centers like Labaid, Popular diagnostics center, Square, Apollo, United and Care Hospitals are providing molecular and cytogenetic tests services in Bangladesh.
It’s a matter of great hope that DNA based specialized molecular diagnostics tests are available under the same roof in DNA Solution Ltd.
As part of their regular activities, a team of health based web portal amarhealth.com has recently visited such a leading molecular lab-- DNA Solution Ltd.
Professor Sharif Akhteruzzaman, chairman of this lab, also professor at Department of Genetic Engineering & Biotechnology, University of Dhaka, shared about the molecular services provided in DNA Solution Ltd.
This prominent DNA expert said, “There are huge possibilities of false-negative or false –positive results in conventional tests but DNA based molecular test can confirm them exactly. This is why the popularity of molecular sector is gradually increasing both in Bangladesh and beyond.”
A good number of Biotechnologist, Molecular biologist, Pharmacist are working here with cutting-edge technologies and most sophisticated equipment like Real-time PCR, Genetic Analyzer etc. to ensure provide premium quality services, he told amarhealth.com.
There are so many services available in DNA Solution Ltd.
Infectious disease test–
Diagnosis of any type of infectious disease like bacterial or viral (hepatitis B, C, Dengue, Chikungunya etc.) available here. It’s important to mention that if we diagnose them at DNA level, we may get an accurate result. Because sometimes we find a false negative or a false positive result in the conventional serological test. Besides, it may take 2/3 days to find the reports if we test them in conventional way. On the other hand, the DNA level test result is found on the first day of the fever. As a result, physicians can start treatment at an early stage resulting less sufferings of patients. However, precocious diagnosis is possible only in DNA test.
Genetic disease test---
Thalassemia is inherited blood disorder characterized by abnormal hemoglobin production. Basically, its genetic disorder inherited from a person's parents. There are two main types, alpha thalassemia and beta thalassemia. Diagnosis may occur before birth through prenatal testing. And the tests are available in DNA level testing which would confirm properly whether the unborn child would be a carrier. Besides, Dawn Syndrome test also possible here before the birth of the baby.
Cancer detection test:
Some sorts of cancers like breast cancer, cervical cancer which are caused by DNA damage, also diagnosed here. To add, Blood Cancers like Acute Myeloid Leukemia (AML), Chronic Myelogenous Leukemia (CML), which are caused by ‘chromosomal abnormality’, also diagnosed in DNA Solution Ltd. very easily.
In order to determine if you are a good candidate for an organ transplant, some tests might be performed at the same time. And all kind of tests are available in this specialized lab.
DNA Relationship testing--
A DNA Relationship testing service is offered by DNA Solution Ltd. that uses a world class method of DNA profiling for paternity, maternity, siblingship and kinship testing. With the use of ultra-modern molecular technology, the testing is performed accurately.
It’s a matter of great hope that a person’s DNA profile remains the same throughout life therefore the analysis can be performed at any age.
Interviewer: Noman Patwary, Photos: Aual Hossain
Controlling dose variation---
In terms of ages, there are only two type of doses for patients in our country. The first one is ‘pediatric dose’ and the second one is ‘adult dose’.
Though the general medicines like paracetamol etc. do not harm much. But there are a good number of medicines that may make serious harm for patients if proper dose is not maintained. Such a medicine is Anticoagulant. Basically, Anticoagulant is given to people at a high risk of getting clots, to reduce their chances of developing serious conditions such as strokes and heart attacks.
Due to variation of genes, a person’s dose is 10 mg while it is double for others.
DNA solution Ltd. has Warfarin Sensitivity Testing. The purpose of this test is to determine whether a patient has genetic variations and is likely to need lower, or less commonly, higher than average doses of the "blood-thinning" drug warfarin.
Non-Invasive Prenatal Testing---
Non-Invasive Prenatal Testing (NIPT) is going to be introduced by DNA solutions ltd in near future. It’s a DNA test on maternal blood to screen pregnancies for the most common fetal chromosome anomalies like Down syndrome, Edwards syndrome and Patau syndrome. Moreover, the gender of the fetus is determined by the same test.
Hopefully, DNA based specialized molecular diagnostic tests would be able to gain more popularity for its affordable quality services in Bangladesh.