Monday, 17 Jun 2019

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Breast cancer drug linked to brain malfunction

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Health Desk-26 Dec’18: A breast cancer drug reveals side-effects, including mood disturbances and memory issues, that impact the brain function in both humans and animals, say researchers.

The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens.

For the study, researchers from the University of Toronto in Canada showed that they administered letrozole to male and female marmosets -- a nonhuman primate model -- for four weeks and observed many behavioural changes including hot flashes and increased anxiety, experienced by women receiving similar treatment.

Findings emphasise the need for further investigation of breast cancer treatments and their effects on the brain, the team noted.