Thursday, 17 Oct 2019

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'Supercool' method triples organ survival, US researchers say

No icon Amar Doctor

Health Desk- 12 Sep 2019: Supercooling human livers to -4C triples the time they can be kept before transplant compared with putting them on ice, US researchers say.

It slows the metabolic rate to prevent damage, Nature Biotechnology reports.

It means organs can be kept viable for more than a day, which researchers say could revolutionise organ transplants.

The next step will be assessing how long supercooled organs function in large animals such as pigs, before moving to human clinical trials.

The team at Massachusetts General Hospital and Harvard Medical School pioneered the technology in rats five years ago.

The animal's tiny livers were chilled while nutrients and oxygen were pumped through the organ's blood vessels.

However, there were challenges going from a 10g (0.35oz) rat liver to a 1.5kg (3lb 5oz) human liver.

Courtesy: BBC Health