Friday, 22 Mar 2019

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Gene-editing extremely damages DNA

No icon Amar Doctor

Health Desk-- 18 July, 2018: A revolutionary gene editing technique hailed as the future of disease eradication and mooted for a Nobel prize may be less precise and cause more cell damage than previously thought, researchers said Monday, reports AFP.

Lab experiments using mouse and human cells revealed that the CRISPR-Cas9 technique “frequently” caused “extensive” gene mutations, a study team reported.          

“This is the first systematic assessment of unexpected events resulting from CRISPR-Cas9 editing,” said Allan Bradley of the Wellcome Sanger Institute in England, where the team conducts research.

The research showed that “changes in the DNA have been seriously underestimated before now,” said Bradley, who co-authored a study.

The study was published in the journal Nature Biotechnology.